Modification of Fully Automated Total Iron-binding Capacity (TIBC) Assay in Serum and Comparison with Dimension TIBC Method

Modification of fully automated total iron-binding capacity (TIBC) assay in serum and comparison with dimension TIBC method.

BACKGROUND We previously reported the development of a fully automated assay for total iron-binding capacity (TIBC) in serum, using a multipurpose automated analyzer. However, this method requires four different reagents and is thus useful only with a limited number of available analyzers. We simplified our original assay and compared the analytical performance of the modified method with that ...

Diagnostic Accuracy of Serum Iron and Total Iron Binding Capacity (TIBC) in Iron Deficiency State.

OBJECTIVE To determine the diagnostic accuracy of serum iron and total iron binding capacity (TIBC) in detection of iron deficiency. STUDY DESIGN Descriptive, analytical study. PLACE AND DURATION OF STUDY Department of Chemical Pathology and Endocrinology, from January 2013 to October 2015. METHODOLOGY Data of 1,815 patients with results of serum iron, TIBC and ferritin from January 2013 ...

New method for determining total iron-binding capacity of serum (TIBC) with radioiron by eliminating iron from transferrin.

Fully automated measurement of total iron-binding capacity in serum.

We established a method for fully automated measurement of total iron-binding capacity (TIBC) in serum without separation of the unbound excess iron after saturating serum transferrin. After saturation of serum transferrin with an excess amount of iron (first step), the unbound iron was eliminated by formation of a complex with ferrozine, which was used as a chromogenic reagent (second step). F...

Serum Ferritin, Iron, TIBC, Hb in male patients with dysglycemia